Abstract" Objective：To investigate the risk factors of enteral nutritional intolerance in intensive care unit(ICU) patients through Meta-analysis.Methods：Literature on enteral nutritional intolerance in ICU patients was reviewed from WanFang Database，CNKI，VIP and CBM.The relevant data were extracted and analyzed with RevMan 5.3 software.Results：A total of 20 articles were included.The results of Meta-analysis showed that intra-abdominal pressure(OR＝3.53，95%CI 2.42-5.16，P<0.000 01)，APACHE Ⅱ score(OR＝2.17，95%CI 1.26-3.74，P=0.005)，application of acid-suppressive drugs(OR＝3.56，95%CI 1.32-9.58，P=0.01)，fasting timegt;72 h(OR＝2.06，95%CI 1.47-2.88，P<0.000 1)，implementation days of enteral nutrition(OR＝4.00，95%CI 3.55-4.45，P<0.000 01)，age(OR＝2.05 ......