AbstractObjective：Tosystematicallyevaluatetheefectofpreventivenegativepresure woundtherapyinpatientsundergoing abdominalsurgery.Methods：Randomizedcontroledtrials(RCTs)ontheefectofpreventivenegativepresure Woundtherapyand standarddressingsinpatientsudergoingabdominalsurgerywereretrievedfromPubMed，WebofSience，EMbase，theCoane Library，CIALKI，WanFangatabse，CB，licalialsndneseCcalTriaegistryCiC)frothtablstf databasestoMay31，O24.ThCchaneriskof-biastolwasusedtoevaluatethequaltyoftheliteratureandRevMan5.3software wasusedforstatisticalaalysis.Results：Atotalof2ricleswereicluded，volving3O5patient.Compardwithsandarddsing， preventive negative pressure wound therapy can reduce the incidence of surgical site infection(OR °leddash 0.56，95%C10.46-0.69， Plt;0.001 ) and seroma(OR =0.45，95%0.29-0.69，Plt;0.001) in patients undergoing abdominal surgery. However，there was no statistically significantdiferenceintheincidenceofincisiondehiscence，hematoma，andlengthofstaybetwen thetwogroupsof patints.

    Conclusions：Existing evidenceshowes that preventive negative presure Wound therapycouldreducethe incidenceof surgicalsite nfection in patients undergoing abdominal surgery. ......