【摘 要】胆囊癌分子基因学研究对寻找胆囊癌的血清标志物以及判断其预后至关重要。本文就胆囊癌的高危因素、病理学路径及分子形态学进行综述，以期为推动胆囊癌临床研究献出微薄之力。

    【关键词】胆囊癌；发育异常；分子病理学

    [Abstract]Molecular genetic studies on gallbladder cancer is essential for identification of serum markers in diagnose of gallbladder cancer and determination of the prognosis.This paper reviews the risk factors， morphology and molecular pathology for gallbladder cancer，to provide reference for further clinical researchon gallbladder cancer.

    [Key words]Gallbladder cancer；dysplasia；molecular pathology

    胆囊癌在发生率上存在着地理学的差异，在印度和智利发生率较高，而在许多西方国家发生率相对较低。高危险因素包括胆石病、感染和胆胰管汇合部发育异常 ......