孕前优生风险因素对新婚和再生育夫妇影响的回顾性分析(1)

http://www.100md.com 2019年3月1日 《中外女性健康研究》 20195

     【摘 要】目的：通過回顾性分析河北省6个项目点孕前优生健康检查中风险因素与妊娠结局的关系，对比新婚组与再生育组在风险因素接触及各项检查指标之间有无差异性存在。方法：选择2014年1月1日至2016年12月31日涉及的6个站点孕前优生检查的新婚夫妇5293对和3528对再生育夫妇进行档案调查、分析，统计对比两组间风险因素的影响。结果：新婚夫妇的总风险检出率为34.6%，再生育夫妇的总风险检出率为51.6%，再生育组的总风险因素检出率明显高于新婚组;新婚组一般风险检出率高于再生育组。在风疹易感等方面，新婚夫妇的风险高于再生育夫妇;再生育组低风险、高风险检出率均高于新婚组;在性传播疾病、生殖道感染、生殖系统疾病、不良孕产史、TSH等方面，再生育组的检出率高于新婚组;经统计学分析P均<0.05。结论：开展孕前优生和婚检是出生缺陷的第一道防线，对新婚和再生育夫妇的风险评估做到各有侧重，个性化的指导，减少不良妊娠结局的发生。

    【关键词】 孕前优生;新婚;再生育;风险因素;回顾性分析

    Retrospective analysis about the influence of risk factors on newly married and rebirth couples in prepregnancy physical examination

    Liu Ran1， Han Yanli2， Zhang Jianping3， Han Hongwei4， Bai Yuxiu5， Gao Zhangquan6

    1.Hebei Jinzhou Maternal and Child Health Planning Service Center， Jinzhou， Hebei 052260;

    2.Family Planning Service Station， Gaocheng District， Shijiazhuang， Hebei 052160;

    3.Hebei Province Xingtang County Family Planning Service Station， Shijiazhuang， Hebei 050600;

    4.Hebei Huanghua Maternal and Child Health Planning Service Center， Huanghua， Hebei 061100;

    5.Family Planning Service Station of Zanhuang County， Hebei Province， Shijiazhuang， Hebei 051230;

    6.Hebei Province Family Planning Science and Technology Institute(Key Laboratory of Family Planning and Health Birth， National Health and Family Planning Commission)， Shijiazhuang， Hebei 050071

    [Abstract] Objective： To analyze the relationship between risk factors and pregnancy outcomes in prepregnancy physical examination at six project sites of Hebei province， and to compare the differences between newlyweds and reproductive groups in risk factors exposure and examination indexes. Methods： From January 1， 2014 to December 31， 2016， 5 293 newlyweds and 3 528 reproductive couples were selected. The influence of risk factors between the two groups was analyzed. Results： The total risk detection rate of newlyweds was 34.6%. The total risk detection rate of reproductive couples was 51.6%. The total rate of risk factors in the reproductive group was significantly higher than the newlyweds. The rate of low risk in the newlyweds was higher than the reproductive group. The detection rate of sexually transmitted diseases， reproductive tract infections， reproductive system diseases， adverse pregnancy and childbirth history， TSH and so on in the reproductive group was higher than the newlyweds group. Conclusion： Prepregnancy physical examination is the first line to defense birth defects. Risk assessment of newlyweds and reproductive couples should be focused on individualized guidance to reduce the incidence of adverse pregnancy outcomes., http://www.100md.com(刘冉 韩彦丽 张建平 韩红伟 白玉秀 高章圈)

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