【摘 要】目的：探究微创手术对结石性胆囊炎患者应激及免疫功能的影响。方法：将我院2015.04～2016.04期间收治的80例结石性胆囊炎患者按随机数字法分为两组。给予观察组腹腔镜微创治疗，给予对照组传统开腹切除术。比较两组在IgA 、IgG、IgM免疫功能指标与CRP、IL-6、TNF-α应激反应指标的变化差异。结果：术后3d，观察组IgA、IgG、IgM恢复情况明显优于对照组(P<0.05)。k术后1天，两组CRP、IL-6、TNF-α比术前有明显的上升(P<0.05)，术后第3天，观察组CRP、IL-6、TNF-α改善幅度明显优于对照组(P<0.05)结论：微创手术在治疗结石性胆囊炎中对机体应激与免疫反应能起到保护性作用，减少术后并发症同时加快术后康复。

    【关键词】微创手术；结石性胆囊炎；免疫功能

    【Abstract】Objective： To explore the effect of minimally invasive surgery on stress and immune function in patients with calculous cholecystitis. Methods： 2015.04～2016.04 in our hospital 80 cases of cholecystitis patients were divided into two groups randomly. The observation group was given laparoscopic minimally invasive treatment ......