[摘要]目的探讨帕罗西汀和认知行为疗法(CBT)治疗女性强迫症病人的效果及其对性功能影响。方法将49例强迫症病人随机分为帕罗西汀组(给予帕罗西汀60 mg/d)和CBT组(给予CBT每周1次，每次45 min，共12次)。于治疗前和治疗12周末，采用耶鲁-布朗强迫症状量表(Y-BOCS)和女性性功能指数问卷(FSFI)评估病人病情和性功能障碍。结果帕罗西汀组病人治疗后性满意度、FSFI和Y-BOCS评分低于治疗前，差异有统计学意义(t=3.196～5.905，Plt;0.01)。CBT组病人治疗后性欲和性高潮评分高于治疗前，差异有统计学意义(t=3.924、2.601，Plt;0.05);FSFI和Y-BOCS评分低于治疗前，差异有统计学意义(t=2.288、5.576，Plt;0.05)。结论CBT治疗女性强迫症病人的效果与帕罗西汀相似，而对性功能的改善优于帕罗西汀。

    [关键词]强迫性障碍;帕罗西汀;认知疗法;治疗结果;性功能障碍

    [中图分类号]R749.91;R493[文献标志码]A[文章编号] 2096-5532(2018)06-0718-04

    CLINICAL EFFECT OF PAROXETINE VERSUS COGNITIVE BEHAVIORAL THERAPY IN TREATMENT OF FEMALE PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDER AND THEIR INFLUENCE ON SEXUAL FUNCTION ""HUANG Fei， JIANG Xiangzhi(Department of Psychiatry， Qingdao Mental Health Center， Qingdao 266034， China)

    [ABSTRACT]ObjectiveTo investigate the clinical effect of paroxetine versus cognitive behavioral therapy (CBT) in the treatment of female patients with obsessive-compulsive disorder (OCD) and their influence on sexual function. MethodsA total of 49 patients with OCD were randomly divided into paroxetine group (60 mg/d) and CBT group (treated with CBT for 45 min once a week ......