[摘要]目的探讨上消化道术后手术部位感染常见的细菌种类及其耐药性。方法回顾性分析2011年1月—2016年2月我院普通外科的113例上消化道术后手术部位感染病人的细菌培养及药敏资料。结果113例病人共送检标本115份，培养出细菌135株，其中革兰阴性杆菌109株(80.7%)，革兰阳性球菌20株(14.8%)，真菌6株(4.4%);常见的感染菌依次为铜绿假单胞菌38株(28.2%)，大肠埃希菌30株(22.2%)，肺炎克雷伯杆菌17株(12.6%)，鲍曼不动杆菌10株(7.4%)，阴沟肠杆菌10株(7.4%)，均为肠道内正常居留菌。上述常见革兰阴性杆菌对一二代头孢类抗生素的耐药率多在50%左右，大肠埃希菌、肺炎克雷伯杆菌及阴沟肠杆菌对亚胺培南、美罗培南的耐药率均较低。结论上消化道术后病人手术部位感染的病原菌以革兰阴性杆菌为主，为控制感染及耐药菌播散，需合理应用抗生素。

    [关键词]外科伤口感染;上胃肠道;消化系统外科手术;细菌;抗药性，微生物

    [中图分类号]R656;R619.3[文献标志码]A[文章编号] 2096-5532(2018)06-0721-04

    ISOLATION AND DRUG RESISTANCE OF BACTERIA IN SURGICAL SITE INFECTION AFTER UPPER GASTROINTESTINAL SURGERY ""NIU Dongguang， LI Chen， FANG Hongchun， "QUAN Lin， LIU Peng， DING Lianan(Gastrointestinal Surgery Department， The Affiliated Hospital of Qingdao University， Qingdao 266100， China)

    [ABSTRACT]ObjectiveTo investigate the bacteria causing surgical site infection after upper gastrointestinal surgery and their drug resistance. MethodsA retrospective analysis was performed for bacterial culture and drug sensitivity data of 113 patients with surgical site infection after upper gastrointestinal surgery who were treated in the Department of General Surgery in our hospital from January 2011 to February 2016. ResultsA total of 115 specimens were collected from these patients. A total of 135 strains were cultured ......