[摘要] 随着科学技术和医学研究的进步，纳米材料在药物载体中发挥着越来越重要的作用。静电纺丝技术为生产纳米纤维最常用的技术之一，静电纺丝纤维因具有比表面积大、孔隙率高等优点，得到研究者的广泛关注。在生物医学领域，多种材料和技术方法被用于制备静电纺丝纤维，可实现理想包封和负载多种药物，通过调整支架对药物的释放，发挥良好的抗癌、抗感染以及诱导细胞分化等作用。本文就载药静电纺丝纤维的研究及应用进展作一综述。

    [关键词] 静电纺丝；纳米纤维；药物载体；药物释放系统

    [中图分类号] R452;R944.9

    [文献标志码] A

    [文章编号] 2096-5532(2023)01-0147-04

    doi：10.11712/jms.2096-5532.2023.59.048

    [网络出版] https：//kns.cnki.net/kcms/detail/37.1517.R.20230308.1034.007.html;2023-03-09 17：02：50

    ADVANCES IN THE RESEARCH AND APPLICATION OF DRUG-LOADED ELECTROSPINNING NANOFIBERS

    YU Chaoqun， LONG Yunze， LIU Xianfeng， WANG Xueyan， LIU Yikai， ZHANG Haining

    (Department of Joint Surgery， Affiliated Hospital of Qingdao University， Qingdao 266100， China)

    ; [ABSTRACT] "With the development of science and medical research， nanomaterials play an increasingly important role in drug delivery. The electrospinning technique is one of the most commonly used methods for fabricating nanofibers， and electrospinning nanofibers have attracted wide attention due to the advantages such as large specific surface area and high porosity. In the field of biomedicine ......