肌肉减少症在胃癌中的研究进展

[摘要]肌肉减少症是一种伴骨骼肌力量、质量减少以及功能状态下降的增龄性综合征。胃癌病人易合并肌肉减少症,严重影响病人的预后。本文就肌肉减少症在胃癌中的诊断和评估、发病机制、对预后影响以及治疗进行综述,为胃癌合并肌肉减少症的防治提供借鉴。
[关键词]肌减少症;胃肿瘤;综述[中图分类号]R735.2[文献标志码]A
[文章编号]20965532(2025)01015405" " doi:10.11712/jms.20965532.2025.61.026[HT]
[开放科学(资源服务)标识码(OSID)]
[网络出版]https://link.cnki.net/urlid/37.1517.R.20250324.1720.002;2025032511:27:15
[Abstract]Sarcopenia is an aging syndrome accompanied by reductions in skeletal muscle strength, mass, and functional status. Gastric cancer patients are often comorbid with sarcopenia, which seriously affects their prognosis. This article reviews the diagnosis, evaluation, and pathogenesis of sarcopenia in gastric cancer, the impact of sarcopenia on prognosis, and the treatment of sarcopenia, in order to provide a reference for the prevention and treatment of gastric cancer with sarcopenia.
2020年,胃癌死亡病例占恶性肿瘤相关死亡的7.7%[1]。胃癌病人具有消化道梗阻、围手术期禁食、营养物质的摄入和吸收受阻等特点,发生营养不良的风险较高,易导致病人合并肌肉减少症(肌少症)。肌少症由ROSENBERG[2]于1989年提出,被定义为一种进行性、广泛性骨骼肌含量减少和功能减退的综合征 ......
您现在查看是摘要页,全文长 22688 字符。