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安罗替尼联合PD-1抑制剂治疗晚期卵巢癌临床转归的影响因素及其预测效能
http://www.100md.com 2025年9月2日 青岛大学学报(医学版) 2025年第3期
     [关键词]卵巢肿瘤;程序性细胞死亡受体1;安罗替尼;治疗结果;影响因素分析[中图分类号] R737.31;R392.1 [文献标志码]A [文章编号] 2096-5532(2025)03-0406-05doi:10.11712/jms.2096-5532.2025.61.091 [开放科学(资源服务)标识码(OSID)][网络出版] https://link.cnki.net/urlid/37.1517.R.20250724.1407.001; 2025-07-2417:18:18

    Influencingfactorsfortreatmentoutcomeofanlotinibcombined withPD-1inibitors inadvanced epithelialovariancancerandtheir predictive eficacyGETan,SHEN Jian,ZHAORong(Pharmacy Departmentof Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 20o025,China)

    [Abstract]ObjectiveTo investigate thefactors influencing the clinicaloutcomeof anlotinib combined with programmed death-1(PD-1)inibitors treatingadvancedepithelialovariancancer(EOC)andtheirpredictiveeficacy.MethodsWedivided 157 patientswithadvancedEOCtreatedwithanlotinibcombinedwithPD-1inhibitorsinourhospitalfromAugust202OtoAugust 2023intogoodoutcome groupand pooroutcomegroup.Basedonthepatients’clinicaland biochemical data,thefactorsaffecting clinicaloutcome wereanalyzed,andtheirpredictiveeficacywasaessed.ResultsHighgradeserouscarcioma,aphsicalsta tus(PS) score of 2 points ......

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