张 耀，李天祥，2，朱 静，张明均，周亚利

    (1.贵州大学化学与化工学院 贵州贵阳 550025； 2.瓮福〔集团〕有限责任公司 贵州福泉 550501)

    湿法磷酸中碘的回收及其在医药中间体制备中的应用

    张耀1，李天祥1，2，朱静1，张明均1，周亚利1

    (1.贵州大学化学与化工学院贵州贵阳550025； 2.瓮福〔集团〕有限责任公司贵州福泉550501)

    摘要碘是一种人体必需的微量元素，同时也是制备无机和有机碘化物的重要原料。概述了湿法磷酸生产中碘的回收方法，并对碘在合成碘代苯胺、碘代苯酚以及碘代苯甲酸类药物中间体中的应用进行了总结。对于湿法磷酸中碘的回收，若料液中碘的含量较低时，一般可选用离子交换法、溶剂萃取法、膜分离法、活性炭吸附法等；若料液中碘的含量较高，可选用沉淀法、浮选法、空气吹出法等。

    关键词碘湿法磷酸工艺医药中间体

    Recovery of Iodine from Wet- Process Phosphoric Acid and Use of Iodine in Preparation of Pharmaceutical Intermediates

    Zhang Yao1, Li Tianxiang1,2, Zhu Jing1, Zhang Mingjun1, Zhou Yali1

    (1.School of Cehmistry and Chemical Engineering, Guizhou UniversityGuizhou Guiyang550025；2.Wengfu 〔Group〕 Co., Ltd.Guizhou Fuquan550501)

    AbstractIodine is a trace element necessary for human body, and it is also an important raw material for preparation of organic and inorganic iodides. Iodine recovery methods from wet- process phosphoric acid are summarized, and the use of iodine in synthesis of pharmaceutical intermediates, such as iodoaniline, iodophenol, iodobenzoic acid, is summed- up. For recovery of iodine from wet- process phosphoric acid, if iodine concentration in feed liquid is low, these methods, including ion exchange method, solvent extraction method, membrane separation method, active carbon absorption method etc. can be chosen generally; while iodine level in feed liquid is higher, precipitation method, flotation method, air blow- out method etc. can be selected. ......