袁泽利，余光勤，罗玉兰，宋文婷

    (遵义医学院 药学院, 贵州 遵义 563099)

    Macrocyclic compounds have attracted increasing interest owing to their role in the understanding of molecular processes occurring in biochemistry, pharmacy, encapsulation,activation and hydrometallurgy[1-4].

    In general, several techniques such as template-assisted[5-6]or preorganization-assisted syntheses combined with the high dilution method[7]are employed for the preparation of desired macrocycles. However, synthesis of the desired macrocyclic compounds sometimes still remains problematic since competitive reactions may occur and result in several kinds of oligomeric compounds[8]. In order to circumvent those problems, people have paid more attention to the new synthetic methods. Organic reactions assisted by microwave irradiation have attracted considerable attention in recent years[9]. Additionally, a noteworthy advantage of modern scientific microwave apparatus is the ability to control reaction parameters such as temperature, pressure and reaction times accurately. So, numerous organic reactions have been performed,i.e., Michael addition, acylation and alkylation reactions,condensations, enzymatic catalysis, rearrangements, oxidations and reducetions, regioselective cycloaddition assisted by microwave irradiation[9]. ......