2019冠状病毒病疫情期间血液肿瘤患儿防控管理的真实世界研究(1)
[摘要]目的：制定并实践2019冠状病毒病(Corona virus disease 2019，COVID-19)疫情期间血液肿瘤患儿的防控管理模式，探讨其真实世界效果。方法：根据COVID-19疫情期间国家公开发布的防控指引，结合广西疫情和临床实际，制定血液肿瘤患儿收治流程;住院期间患儿、陪人、环境、物品管理;工作人员管理;血液肿瘤患儿居家隔离治疗的防控措施。结果：2020-01-01至2020-03-31期间，80例150人次住院血液肿瘤患儿(包括29例新发血液肿瘤患儿)和106例居家隔离治疗患儿均未出现新型冠状病毒感染。结论： COVID-19疫情期间制定并严格执行防控管理模式，可保障流行病真实世界中血液肿瘤患儿安全。
[关键词]2019冠状病毒病;儿童;血液肿瘤;防控
【中图分类号】R552 【文献标识码】A 【文章编号】2107-2306(2020)02-256-02
Real-world study on prevention and control of children with hematological tumors during the epidemic of Corona virus disease 2019
Li Xinye， Ma Hongyan， Lu Yuanfeng， Feng Dongdong， Song Kunling， Xie Peizhi， Pan Xingjiang， Dai Yan△
Department of Pediatrics， the People′s Hospital of Guangxi Zhuang Autonomous Region， 530021， Nanning， China
[Abstract]Objective：To develop and implement a model for the prevention and control of children with hematological tumors during the epidemic of Corona virus disease 2019(COVID-19)， and then to explore its real-world effects. Methods： According to publicly issued prevention and control guidelines during the epidemic of COVID-19， combined with the epidemic situation and clinical practice in Guangxi province， prevention and control measures have been formulated， including the admission process of new and original hematological tumors， management of environment， articles and companions during hospitalization， medical staff management， measures of home isolation treatment for out of hospital tumors. Results： From January 1， 2020 to March 31， 2020， A total of 80 patients with hematological tumors were admitted to our department for 150 person times， 29 new patients with hematological tumors were hospitalized， and 106 children were isolated at home for treatment. No infection was found in hospitalized children and children outside the hospital. Conclusion： During the COVID-19 epidemic， to develop and implement reasonable management measures can effectively prevent and control the safety of children with hematological tumors.
[Key words]Corona virus disease 2019; Children; Hematological tumor; Prevention
2019年12月以來，湖北省武汉市爆发COVID-19[1]并波及全国，传染性强、波及面广、疫情复杂。新型冠状病毒肺炎患者和无症状感染者是传染源，主要传播途径为呼吸道飞沫传播和接触传播，潜伏期为1-14天，多为3-7天，人群普遍易感，包括儿童及婴幼儿，家庭聚集性是COVID-19的流行特征之一[2]。近期武汉报道115例新冠肺炎感染患儿临床症状轻微，3例危重型病例均合并其他疾病，包括1例8岁男孩合并急性淋巴细胞白血病及化疗后骨髓抑制[3]。
血液肿瘤患儿诊治专业性强、周期长、难度大、费用高，需要定期往返具有救治条件的医疗中心接受专业治疗，是COVID-19的高危人群。如何保障危重患儿的及时救治，避免因疫情中断化疗影响疾病最终转归，做好医院、往返及居家治疗的安全衔接，构建疫情下儿童血液肿瘤管理体系是儿童血液肿瘤医师面临的新挑战。因此，探索COVID-19疫情期间血液肿瘤患儿的管理策略，做好真实世界疫情防控极为迫切;长远来看，传染病流行期间，针对特殊高危儿童构建安全高效的流行病学防控措施，具有非常深远的现实意义。, http://www.100md.com(李新叶 马红艳 陆元奉 宋坤岭 代艳△)
[关键词]2019冠状病毒病;儿童;血液肿瘤;防控
【中图分类号】R552 【文献标识码】A 【文章编号】2107-2306(2020)02-256-02
Real-world study on prevention and control of children with hematological tumors during the epidemic of Corona virus disease 2019
Li Xinye， Ma Hongyan， Lu Yuanfeng， Feng Dongdong， Song Kunling， Xie Peizhi， Pan Xingjiang， Dai Yan△
Department of Pediatrics， the People′s Hospital of Guangxi Zhuang Autonomous Region， 530021， Nanning， China
[Abstract]Objective：To develop and implement a model for the prevention and control of children with hematological tumors during the epidemic of Corona virus disease 2019(COVID-19)， and then to explore its real-world effects. Methods： According to publicly issued prevention and control guidelines during the epidemic of COVID-19， combined with the epidemic situation and clinical practice in Guangxi province， prevention and control measures have been formulated， including the admission process of new and original hematological tumors， management of environment， articles and companions during hospitalization， medical staff management， measures of home isolation treatment for out of hospital tumors. Results： From January 1， 2020 to March 31， 2020， A total of 80 patients with hematological tumors were admitted to our department for 150 person times， 29 new patients with hematological tumors were hospitalized， and 106 children were isolated at home for treatment. No infection was found in hospitalized children and children outside the hospital. Conclusion： During the COVID-19 epidemic， to develop and implement reasonable management measures can effectively prevent and control the safety of children with hematological tumors.
[Key words]Corona virus disease 2019; Children; Hematological tumor; Prevention
2019年12月以來，湖北省武汉市爆发COVID-19[1]并波及全国，传染性强、波及面广、疫情复杂。新型冠状病毒肺炎患者和无症状感染者是传染源，主要传播途径为呼吸道飞沫传播和接触传播，潜伏期为1-14天，多为3-7天，人群普遍易感，包括儿童及婴幼儿，家庭聚集性是COVID-19的流行特征之一[2]。近期武汉报道115例新冠肺炎感染患儿临床症状轻微，3例危重型病例均合并其他疾病，包括1例8岁男孩合并急性淋巴细胞白血病及化疗后骨髓抑制[3]。
血液肿瘤患儿诊治专业性强、周期长、难度大、费用高，需要定期往返具有救治条件的医疗中心接受专业治疗，是COVID-19的高危人群。如何保障危重患儿的及时救治，避免因疫情中断化疗影响疾病最终转归，做好医院、往返及居家治疗的安全衔接，构建疫情下儿童血液肿瘤管理体系是儿童血液肿瘤医师面临的新挑战。因此，探索COVID-19疫情期间血液肿瘤患儿的管理策略，做好真实世界疫情防控极为迫切;长远来看，传染病流行期间，针对特殊高危儿童构建安全高效的流行病学防控措施，具有非常深远的现实意义。, http://www.100md.com(李新叶 马红艳 陆元奉 宋坤岭 代艳△)