Lvkumr VupplptiRvihnirn VelyumK.F.H.Nzeer AhmeSowmy CherukuriBhskr Rey Kesvn

    a Center for Nanobiotechnology,Sri Venkateswara College of Pharmacy,RVS Nagar,Chittoor 517127,AP,India

    b NIPER,Raja S.C.Mullick Road,Jadavpur,Kolkata 700032,India

    c Center for Research and Innovation,Asia Metropolitan University,Cheras 43200,Malaysia

    d Department of Pharmaceutics,RIPER,Anantapuram 515721,AP,India

    Abstract The present investigation was considered in arraying of antidiabetic and antioxidant activity from dietary fl vonoid loaded fraction of Acanthophora spicifera (A. spicifera, Family: Rhodomelaceae) on streptozotocin (STZ) induced oxidative stress rats. The testings were acted upon male rats,which were alienated into fi e groups:control group,diabetic group(single dose of 65 mg/kg,streptozotocin(STZ)i.p.),diabetic with insulin(6 IU),and diabetic with fl vonoid rich fraction groups(FRF)at 50 and 100 mg/kg body weight,given orally for 21 days.The blood glucose level was determined at different week intermissions.The antioxidant consequences of FRF on STZ-induced diabetic rats were determined by the estimations of the oxidative stress marker like malonyldialdehyde and antioxidant enzymes such as superoxide dismutase,catalase and glutathione in tissue homogenates of heart, liver and kidney. FRF treatment of diabetic rats significantl (P1. Introduction ......