《基因进展》.2006年.第10期

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• The chicken talpid3 gene encodesa novel protein essentialfor Hedgehog signaling
• Imprinting mechanisms—it only takes two
• Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes
• ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth
• MOZ is essential for maintenance of hematopoietic stem cells
• Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1
• Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes
• Keratin 17 modulates hair follicle cycling in a TNF-dependent fashion
• DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A
• Loss of transforming growth factor- type II receptor promotes metastatic head-and-neck squamous cell carcinoma
• Genetics and biology of pancreatic ductal adenocarcinoma
• Fertility versus disease resistance, a hard choice
• Nucleolar dominance: a model for rRNA gene silencing
• SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
• Promoter mutations of an essential gene for pollen development result in disease resistance in rice
• Erasure of histone acetylation by Arabidopsis HDA6 mediates large-scale gene silencing in nucleolar dominance