《血液学杂志》.2005年.第11期

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• The splenic microenvironment is a source of proangiogenesis/inflammatory mediators accelerating the expansion of murine erythroleukemic cell
• Multifunctional role of erk5 in multiple myeloma
• A novel CDK inhibitor, CYC202(R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved
• B-Raf–dependent expression of vascular endothelial growth factor–A in Kaposi sarcoma–associated herpesvirus-infected human B cells
• Asparagine synthetase expression is linked with L-asparaginase resistance in TeL-AML1–negative but not TeL-AML1–positive pediatric acute lym
• Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study
• The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
• Leukemias following retroviral transfer of multidrug resistance 1(MDR1) are driven by combinatorial insertional mutagenesis
• Tyrosine phosphatase SHP-1 acts at different stages of development to regulate hematopoiesis
• Identification and characterization of undifferentiated mast cells in mouse bone marrow
• Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2
• A systematic scan of interactions with tyrosine motifs in the erythropoietin receptor using a mammalian 2-hybrid approach
• Omenn syndrome due to ARTeMIS mutations
• Induction of tumor NK-cell immunity by anti-CD69 antibody therapy
• A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
• Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome
• TeF, an antiapoptotic bZIP transcription factor related to the oncogenic e2A-HLF chimera, inhibits cell growth by down-regulating expression
• A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival
• Azaspirane(N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow m
• Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VeGF
• Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP
• Leukocyte migration and graft-versus-host disease
• Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
• Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells
• Constitutive homing of mast cell progenitors to the intestine depends on autologous expression of the chemokine receptor CXCR2
• Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in mu
• Sema4D induces angiogenesis through Met recruitment by Plexin B1
• Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion
• Thrombin-catalyzed activation of factor VIII with His substituted for Arg372 at the P1 site
• Selective impairment of platelet activation to collagen in the absence of GATA1
• A proportion of patients with lymphoma may harbor mutations of the perforin gene
• Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow
• Thrombopoietin enhances expression of vascular endothelial growth factor(VeGF) in primitive hematopoietic cells through induction of HIF-1
• Failure of SCID-X1 gene therapy in older patients
• An inducible caspase 9 safety switch for T-cell therapy
• endothelial apoptosis induced by inhibition of integrins v3 and v5 involves ceramide metabolic pathways
• Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting
• Identification and characterization of circulating human transitional B cells
• SAP controls the cytolytic activity of CD8+ T cells against eBV-infected cells
• Negative thymocyte selection to HeRV-K18 superantigens in humans
• Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cell
• New approaches for preventing and treating chronic graft-versus-host disease
• The 3 subunit of the integrin IIb3 regulates IIb-mediated outside-in signaling
• Systemic protein delivery by muscle-gene transfer is limited by a local immune response
• Constitutive mobilization of CD34+ cells into the peripheral blood in idiopathic myelofibrosis may be due to the action of a number of prote
• Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia
• Redox active plasma iron in C282Y/C282Y hemochromatosis
• AML1-FOG2 fusion protein in myelodysplasia
• Identification of a transiently exposed Ve-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature