《血液学杂志》.2005年.第12期

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• A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocyti
• HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation
• CLL, but not normal, B cells are dependent on autocrine VeGF and 41 integrin for chemokine-induced motility on and through endothelium
• Intronic splicing of hyaluronan synthase 1(HAS1): a biologically relevant indicator of poor outcome in multiple myeloma
• Myelodysplasia and acute myeloid leukemia following therapy for indolent lymphoma with fludarabine, mitoxantrone, and dexamethasone(FND) pl
• Fibromodulin, an extracellular matrix protein: characterization of its unique gene and protein expression in B-cell chronic lymphocytic leuk
• Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion pro
• Deregulation of proteins involved in iron metabolism in hepcidin-deficient mice
• Platelet activation in cystic fibrosis
• Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackf
• An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone:
• A classification system for cross-reactive material-negative factor XI deficiency
• High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of th
• Angiopoietin-1 promotes LYVe-1-positive lymphatic vessel formation
• Angiopoietin-1 promotes lymphatic sprouting and hyperplasia
• Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1 in the circulation
• Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis
• Intracellular interaction of von Willebrand factor and factor VIII depends on cellular context: lessons from platelet-expressed factor VIII
• Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo
• The hydration state of human red blood cells and their susceptibility to invasion by Plasmodium falciparum
• Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA ge
• emergent autoimmunity in graft-versus-host disease
• Copper-dependent activation of hypoxia-inducible factor(HIF)-1: implications for ceruloplasmin regulation
• Hodgkin disease to Hodgkin lymphoma: biologic insights and therapeutic potential
• Phenotypic characterization of the human myeloma cell growth fraction
• Lnk inhibits erythropoiesis and epo-dependent JAK2 activation and downstream signaling pathways
• Src homology 2 domain-containing inositol-5-phosphatase 1(SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosph
• expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors
• Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients
• Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4(CD244)
• Ontogeny of CD4+CD25+ regulatory/suppressor T cells in human fetuses
• Pharmacogenetics of outcome in children with acute lymphoblastic leukemia
• Gaucher disease and cancer incidence: a study from the Gaucher Registry
• Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential
• Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
• Fusion of eML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32)
• Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immun
• Assessment of treatment-related myelodysplastic syndromes and acute myeloid leukemia in patients with non-Hodgkin lymphoma treated with tosi
• CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in
• Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic develo
• The homeobox gene HeX regulates proliferation and differentiation of hemangioblasts and endothelial cells during eS cell differentiation
• Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway
• Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive
• Farnesyltransferase inhibitor R115777(Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhib
• Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status
• Role of selectins in the triggering, growth, and dissemination of T-lymphoma cells: implication of L-selectin in the growth of thymic lympho
• Cyclooxygenase-2(COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome
• Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells