《血液学杂志》.2005年.第15期

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• Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stage
• The tumor suppressor TSLC1/NeCL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM
• T/B lineage choice occurs prior to intrathymic Notch signaling
• RNA interference in biology and disease
• TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment
• HFe cross-talks with the MHC class I antigen presentation pathway
• Impaired interferon- production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma
• efficient marking of human cells with rapid but transient repopulating activity in autografted recipients
• Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients
• Long-term outcome of treatment of anemia in MDS with erythropoietin and G-CSF
• BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients
• engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1–infected lymphocytes
• Nonhemolytic antibody-induced loss of erythrocyte surface antigen
• In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets
• Immunoglobulin gene analysis reveals 2 distinct cells of origin for eBV-positive and eBV-negative Burkitt lymphomas
• essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia
• Repressible transgenic model of NRAS oncogene–driven mast cell disease in the mouse
• Production and characterization of erythropoietic protoporphyric heterodimeric ferrochelatases
• Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin
• Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
• A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress
• CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients
• Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV
• Negative regulation of platelet function by a secreted cell repulsive protein, semaphorin 3A
• Ly49 and CD94/NKG2 receptor acquisition by NK cells does not require lymphotoxin- receptor expression
• A single amino acid change, A91V, leads to conformational changes that can impair processing to the active form of perforin
• Seliciclib(CYC202 or R-roscovitine), a small-molecule cyclin-dependent kinase inhibitor, mediates activity via down-regulation of Mcl-1 in
• Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance
• Nuclear expression of BCL10 or nuclear factor kappa B helps predict Helicobacter pylori–independent status of low-grade gastric mucosa–assoc
• Characterization of the role of CaMKI-like kinase(CKLiK) in human granulocyte function
• Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase
• IL-6 blocks a discrete early step in lymphopoiesis
• egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation
• LDL receptor cooperates with LDL receptor–related protein in regulating plasma levels of coagulation factor VIII in vivo
• CD144(Ve-cadherin) is transiently expressed by fetal liver hematopoietic stem cells
• Acute myeloid leukemia bearing cytoplasmic nucleophosmin(NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation
• Rituximab prevents recurrence of thrombotic thrombocytopenic purpura: a case report
• B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis
• Localization of ADAMTS13 to the stellate cells of human liver
• The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic sign
• Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct fr
• Conservation of unique cell-surface CD antigen mosaics in HIV-1–infected individuals
• Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states
• Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype
• Identification and characterization of epitopes of the receptor for hyaluronic acid–mediated motility(RHAMM/CD168) recognized by CD8+ T cel
• PF4/heparin complexes are T cell–dependent antigens
• Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog
• A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation
• Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 my
• A critical function for B-Raf at multiple stages of myelopoiesis