《核酸研究》.2005年.第18期

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• The essential WD-repeat protein Rsa4p is required for rRNA processing
• Two major branches of anti-cadmium defense in the mouse: MTF-1/metallo
• Dominant-negative mutant phenotypes and the regulation of translation
• Molecular beacons as probes of RNA unfolding under native conditions
• The physical determinants of the DNA conformational landscape: an anal
• Application of single molecule technology to rapidly map long DNA and
• Conformation, protein recognition and repair of DNA interstrand and in
• Reduced representation bisulfite sequencing for comparative high-resol
• Improvement in protein functional site prediction by distinguishing st
• Guanine tetraplex topology of human telomere DNA is governed by the nu
• Switching DNA-binding specificity by unnatural amino acid substitution
• Pyrene is highly emissive when attached to the RNA duplex but not to t
• The RING finger ATPase Rad5p of Saccharomyces cerevisiae contributes t
• Structural insights into abasic site for Fpg specific binding and cata
• Experimental comparison and cross-validation of the Affymetrix and Ill
• A genome-wide survey demonstrates widespread non-linear mRNA in expres
• Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing s
• Atomic force microscopy shows that vaccinia topoisomerase IB generates
• Abundance of correctly folded RNA motifs in sequence space, calculated
• Use of altered-specificity binding Oct-4 suggests an absence of plurip
• Depletion of TDP 43 overrides the need for exonic and intronic splicin
• Predicting candidate genomic sequences that correspond to synthetic fu
• Integrative elements for Bacillus subtilis yielding tetracycline-depen
• Shotgun haplotyping: a novel method for surveying allelic sequence var
• A bi-functional siRNA construct induces RNA interference and also prim
• Transformation of expression intensities across generations of Affymet
• Miniature RT–PCR system for diagnosis of RNA-based viruses
• An ES cell system for rapid, spatial and temporal analysis of gene fun
• A highly sensitive selection method for directed evolution of homing e
• A simple method for displaying recalcitrant proteins on the surface of
• Partial 13C isotopic enrichment of nucleoside monophosphates: useful r
• Protein–DNA binding specificity predictions with structural models
• Chemical synthesis and thermodynamic characterization of oxanine-conta
• DNA topoisomerase II interacts with Lim15/Dmc1 in meiosis
• Specificity prediction of adenylation domains in nonribosomal peptide
• Draft versus finished sequence data for DNA and protein diagnostic sig
• Specific function of a plastid sigma factor for ndhF gene transcriptio
• Alternative splicing and nonsense-mediated mRNA decay regulate mammali
• Function of the ribosomal E-site: a mutagenesis study
• Induction of unique structural changes in guanine-rich DNA regions by
• The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 an
• Zinc finger nucleases: custom-designed molecular scissors for genome e
• 8-Oxoguanine incorporation into DNA repeats in vitro and mismatch reco
• Facilitation of a structural transition in the polypurine/polypyrimidi
• Rapid detection of genomic imbalances using micro-arrays consisting of
• Improved methods for the generation of human gene knockout and knockin
• Gene CATCHR—Gene Cloning And Tagging for Caenorhabditis elegans using
• Proximity ligation assays with peptide conjugate ‘burrs’ for the sensi
• Method for multiplex cellular detection of mRNAs using quantum dot flu