《联合生物学》.2005年.第7期

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• Hypoxia-inducible factor 1 is a new target of microphthalmia-associated transcription factor(MITF) in melanoma cells
• Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca2+-dependent signaling cascade
• Early encounters of a nascent membrane protein : specificity and timing of contacts inside and outside the ribosome
• Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor–B activation in muramyl dipeptide recognition
• The c-SMAC : sorting it all out(or in)
• It's HIP to be a hub : new trends for old-fashioned proteins
• Decoding Ca2+ signals : a question of timing
• A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes
• Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer
• Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells
• Proteomic analysis of a eukaryotic cilium
• A microtubule-dependent zone of active RhoA during cleavage plane specification
• TGF- maintains dormancy of prostatic stem cells in the proximal region of ducts
• Hydrogen peroxide regulation of endothelial exocytosis by inhibition of N-ethylmaleimide sensitive factor
• Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1–MEK–JNK signal transduction pathway during metabolic oxid
• Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism
• A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid–induced neuronal differentiation
• JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3
• Src-like adaptor protein down-regulates T cell receptor(TCR)–CD3 expression by targeting TCR for degradation
• Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis
• Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway
• SNAREs can promote complete fusion and hemifusion as alternative outcomes
• The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria
• The nuclear pore complex–associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly
• Meiotic telomere clustering requires actin for its formation and cohesin for its resolution
• Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
• Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors
• FcRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane
• CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+