《细胞学杂志》.2003年.第2期

基础医学

• FAK induces expression of Prx1 to promote tenascin-C–dependent fibrobl
• Control of axon elongation via an SDF-1/Rho/mDia pathway in cultured c
• Pointed-end capping by tropomodulin3 negatively regulates endothelial
• Shear stress–induced endothelial cell polarization is mediated by Rho
• Defining desmosomal plakophilin-3 interactions
• Aurora B puts chromosomes in their place
• To grow or to shrink...
• Reconstituting a chloroplast transport system
• ROS for your roots
• Say NO to insulin
• Choosing replication origins
• CSC-1 : a subunit of the aurora b kinase complex that binds to the sur
• Conserving synaptic weight
• H. pylori mobilizes cells
• Toxoplasma uses tough love
• Active repression by unliganded retinoid receptors in development : le
• Calcium waves in membrane fusion
• Different degrees of lever arm rotation control myosin step size
• The small molecule Hesperadin reveals a role for Aurora B in correctin
• LST8 negatively regulates amino acid biosynthesis as a component of th
• Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family o
• Sim4 : a novel fission yeast kinetochore protein required for centrome
• Identification of XMAP215 as a microtubule-destabilizing factor in Xen
• Tumor cells get primitive
• Binding of an ankyrin-1 isoform to obscurin suggests a molecular link
• Rejection and killing, without MPR
• An interaction that gets things started
• Taking close-ups of a rafting trip
• Direct visualization of Ras proteins in spatially distinct cell surfac
• Tenascin-C signaling through induction of 14-3-3 tau
• Spatio-temporal activation of caspase revealed by indicator that is in
• Compensation mechanism in tumor cell migration : mesenchymal–amoeboid
• The coiled-coil membrane protein golgin-84 is a novel rab effector req
• EpsinR : an AP1/clathrin interacting protein involved in vesicle traff
• RhoA is required for cortical retraction and rigidity during mitotic c
• HA95 and LAP2? mediate a novel chromatin–nuclear envelope interaction
• Traffic-independent function of the Sar1p/COPII machinery in proteasom
• Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion an
• Venus dye trap catches executioners
• A clathrin/dynamin- and mannose-6-phosphate receptor–independent pathw
• Getting specific about polarized sorting
• Weaklings unite to reorganize cell
• Transcription keeps it simple
• Laminin-2 on the brain
• An early warning system for DNA damage
• Desmosomes in a tangle
• Flies fight famine
• Binding takes cooperation
• Lymphatic endothelium : morphological, molecular and functional proper
• Sorting it out : AP-2 and alternate clathrin adaptors in endocytic car
• Architecture of the budding yeast kinetochore reveals a conserved mole
• Clathrin promotes incorporation of cargo into coated pits by activatio
• BPAG1n4 is essential for retrograde axonal transport in sensory neuron
• Impairment of LTD and cerebellar learning by Purkinje cell–specific ab
• Herpes simplex virus triggers activation of calcium-signaling pathways
• NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclea
• The Rab8 GTPase selectively regulates AP-1B–dependent basolateral tran
• Loss of keratin 6(K6) proteins reveals a function for intermediate fi
• Talin1 is critical for force-dependent reinforcement of initial integr
• Integrin-linked kinase is required for laminin-2–induced oligodendrocy
• A dual-functional paramyxovirus F protein regulatory switch segment :
• Rap1 translates chemokine signals to integrin activation, cell polariz
• Regulation of ? cell glucokinase by S-nitrosylation and association wi
• Distinct in vivo roles for double-stranded RNA-binding domains of the
• Aurora B couples chromosome alignment with anaphase by targeting BubR1
• Spatial distribution and specification of mammalian replication origin
• Helicobacter pylori CagA protein targets the c-Met receptor and enhanc
• YHR150w and YDR479c encode peroxisomal integral membrane proteins invo
• Dual function of Slit2 in repulsion and enhanced migration of trunk, b
• Activity of Rho-family GTPases during cell division as visualized with
• Homer 2 tunes G protein–coupled receptors stimulus intensity by regula
• Critical roles for the COOH-terminal NITY and RGT sequences of the int
• Epstein-Barr virus LMP1 blocks p16INK4a–RB pathway by promoting nuclea
• Epstein-Barr virus LMP1 blocks p16INK4a–RB pathway by promoting nuclea
• The AP-1A and AP-1B clathrin adaptor complexes define biochemically an
• The kinase knows
• Formation of stacked ER cisternae by low affinity protein interactions
• DNA damage-induced replication arrest in Xenopus egg extracts
• Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of s
• Akt activation disrupts mammary acinar architecture and enhances proli
• Role of the pleckstrin homology domain of PLC1 in its interaction with
• Nodal-dependent Cripto signaling promotes cardiomyogenesis and redirec
• Regulation of TrkB receptor tyrosine kinase and its internalization by
• Desulfation on the cell surface
• Neural cells turn and run
• Sticky transmission
• Nervous picket fences
• Activation by reduction
• Doing the CDC20 shuffle
• Kicking out antiviral proteins
• Rho activation patterns after spinal cord injury and the role of activ
• Proposed legislation supports an untested publishing model
• Vacuole membrane fusion : V0 functions after trans-SNARE pairing and i
• Alternating metabolic pathways in NGF-deprived sympathetic neurons aff
• Polyamines play a critical role in the control of the innate immune re
• QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfa
• A loss, or two gains?
• A building block of two organelles
• Neural cells turn and run
• The cytoplasmic domain of the Plasmodium falciparum ligand EBA-175 is
• A novel role for dp115 in the organization of tER sites in Drosophila
• PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK act
• Regulation of phospholipase D1 subcellular cycling through coordinatio