《细胞学杂志》.2004年.第2期

基础医学

• A conserved protein interaction network involving the yeast MAP kinase
• Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2
• Sinuous is a Drosophila claudin required for septate junction organiza
• How insulin signals globally and acts locally
• FoxO3a regulates erythroid differentiation and induces BTG1, an activa
• Lethargic mitochondria are left out
• Next vesicle SNAP'd up
• Tracking transcripts
• Rafting across polarized cells
• Telomeres together
• Myc conquers all
• Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains i
• Rab13 regulates PKA signaling during tight junction assembly
• Alternative topogenesis of Mgm1 and mitochondrial morphology depend on
• Nuclear RNP complex assembly initiates cytoplasmic RNA localization
• E-cadherin evades endocytosis
• FAK and paxillin : regulators of N-cadherin adhesion and inhibitors of
• Reprogramming by virus
• Mini inhibition
• Relocation of Aurora B from centromeres to the central spindle at the
• Tugging and pulling in asymmetric cell divisions
• One cyclin for adult neurogenesis
• A chaperone feels the heat
• Uncooperative immune cells
• Cells have a bubbly look
• VASP comet sightings
• Getting the message across, STAT! Design principles of a molecular sig
• Insulin keeps time
• Loss of negative regulation by Numb over Notch is relevant to human br
• The critical role of cyclin D2 in adult neurogenesis
• Coordinating cytoskeletal tracks to polarize cellular movements
• Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the
• Distinct molecular forms of ?-catenin are targeted to adhesive or tran
• Atypical protein kinase C(PKC/) is a convergent downstream target of
• A divergent canonical WNT-signaling pathway regulates microtubule dyna
• Intraflagellar transport(IFT) cargo : IFT transports flagellar precur
• Physical and functional interaction of the active zone proteins, CAST,
• SNAREs drum up calcium
• Conjunction of junctions goes beyond function
• More than one way to skin a phagosome
• Cell-to-cell transport of proteins and fluorescent tracers via plasmod
• Essential role of MARCKS in cortical actin dynamics during gastrulatio
• How to terminate a shmoo
• Regulation of polarized growth initiation and termination cycles by th
• Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lum
• Ordered proteolysis in anaphase inactivates Plk1 to contribute to prop
• One protein, two pools
• Vesicle biogenesis potentiation
• A transmigratory cup in leukocyte diapedesis both through individual v
• Slipping through the middle
• Interaction of Brn3a and HIPK2 mediates transcriptional repression of
• The forces that position a mitotic spindle asymmetrically are tethered
• Differential contribution of Bud6p and Kar9p to microtubule capture an
• Endothelial barrier disruption by VEGF-mediated Src activity potentiat
• Defective function of GABA-containing synaptic vesicles in mice lackin
• The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate t
• The 4q subtelomere harboring the FSHD locus is specifically anchored w
• Roles of p-ERM and Rho–ROCK signaling in lymphocyte polarity and uropo
• UCS protein Rng3p activates actin filament gliding by fission yeast my
• Decreased apoptosome activity with neuronal differentiation sets the t
• Integrins direct Src family kinases to regulate distinct phases of oli
• Novel signaling pathways mediating reciprocal control of keratinocyte
• Another passenger on chromosomes
• Loopy for telomeres
• Integrins talk to N-cadherin
• A synaptic scaffold quiets T cells
• Xylogen makes plant channels
• Flat-out pushing by actin
• Cohesin gets pushed around
• Synaptotagmins are trafficked to distinct subcellular domains includin
• Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins
• Cortactin and Crk cooperate to trigger actin polymerization during Shi
• Vav GEFs are required for ?2 integrin-dependent functions of neutrophi
• Roles played by a subset of integrin signaling molecules in cadherin-b
• Discs large(Dlg1) complexes in lymphocyte activation
• Closed chromatin loops at the ends of chromosomes
• The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regula
• novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast
• Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate recepto
• PKCs pick through Ca2+
• Arpless comets are fascin-ating
• ZIP kinase is responsible for the phosphorylation of myosin II and nec
• Long-term modulation of mitochondrial Ca2+ signals by protein kinase C
• F1F0 ATP synthase subunit c is a substrate of the novel YidC pathway f
• Sequential exocytosis of insulin granules is associated with redistrib
• Fascin-mediated propulsion of Listeria monocytogenes independent of fr
• The role of Cdc6 in ensuring complete genome licensing and S phase che
• Mesenchymal–epithelial interactions in the skin : increased expression
• Being intolerant of tumors
• Get out! And don't come back!