《细胞学杂志》.2004年.第4期

基础医学

• A primordial mover for sphingolipids
• Protein splicing for immunity
• Yeast dies for a noble cause
• Inflexibility in motion
• Nudel functions in membrane traffic mainly through association with Li
• Apoptotic mitochondria blow a fuse
• Winding and unwinding ATP synthase
• Breathe, then breed
• Quantitation of mitochondrial dynamics by photolabeling of individual
• Greatwall kinase : a nuclear protein required for proper chromosome co
• Cells on Parade : The American Society for Cell Biology San Francisco,
• Nanofibers have the right stuff
• Amylin inhibits bone resorption while the calcitonin receptor controls
• Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and
• Michael Klemba, Wandy Beatty, Ilya Gluzman, and Daniel E. Goldberg
• In Candida albicans, the Nim1 kinases Gin4 and Hsl1 negatively regulat
• Fingers lay fibers
• Slingshot to the lamellipod
• Geminin halts DNA synthesis
• Sticky sugar
• Tilt back to turn left
• NG2+ cells feed the brain
• Coalignment of plasma membrane channels and protrusions(fibripositors
• Carbohydrate–carbohydrate interaction provides adhesion force and spec
• MuSK is required for anchoring acetylcholinesterase at the neuromuscul
• NG2-expressing cells in the subventricular zone are type C–like cells
• Pathology of a mouse mutation in peripheral myelin protein P0 is chara
• Mitochondria move in on calcium
• Palindromic protection
• SOS needs help getting active
• Invadolysin opens many doors
• Ubiquitin charging of human class III ubiquitin-conjugating enzymes tr
• Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth co
• Invadolysin : a novel, conserved metalloprotease links mitotic structu
• Pex7p translocates in and out of peroxisomes in Saccharomyces cerevisi
• Control of mitochondrial motility and distribution by the calcium sign
• SPOTS : signaling protein oligomeric transduction structures are early
• Phosphorylation of paxillin by p38MAPK is involved in the neurite exte
• Polarity and proliferation are controlled by distinct signaling pathwa
• Metabolism as a production line
• How to become a generalist again
• Pulling the spindle into shape
• Loss of Geminin induces rereplication in the presence of functional p5
• A pathway of neuregulin-induced activation of cofilin-phosphatase Slin
• 53BP1 is required for class switch recombination
• Mammalian Fat1 cadherin regulates actin dynamics and cell–cell contact
• Woodring, P.J., T. Hunter, and J.Y.J. Wang. 2003. Regulation of F-acti
• Van Parijs, L., Y. Refaeli, J.D. Lord, B.H. Nelson, A.K. Abbas, and D.
• Affixin interacts with -actinin and mediates integrin signaling for re
• Srinivasa Subramaniam, Ute Zirrgiebel, Oliver von Bohlen und Halbach,
• Andreas Wodarz, Andreas Ramrath, Alexandra Grimm, and Elisabeth Knust
• ES cells without teratomas
• In vivo monitoring of Ca2+ uptake into mitochondria of mouse skeletal
• Endocytotic elimination and domain-selective tethering constitute a po
• T cell receptor antagonism interferes with MHC clustering and integrin
• Radixin deficiency causes deafness associated with progressive degener
• Esophageal muscle physiology and morphogenesis require assembly of a c
• Dynein/dynactin regulate metaphase spindle length by targeting depolym
• Dynamic targeting of the replication machinery to sites of DNA damage
• Raf-1 activation disrupts its binding to keratins during cell stress
• The KinI kinesin Kif2a is required for bipolar spindle assembly throug
• Topoisomerase II and histone deacetylase inhibitors delay the G2/M tra
• Chfr acts with the p38 stress kinases to block entry to mitosis in mam
• Mouse centric and pericentric satellite repeats form distinct function
• AMSH is an endosome-associated ubiquitin isopeptidase
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• Junctate is a key element in calcium entry induced by activation of In
• Ubiquitin stripping
• How meals become bones
• Boning up on JunB
• Capping protein binding to actin in yeast : biochemical mechanism and
• Promyelocytic leukemia nuclear bodies associate with transcriptionally
• Chronological aging leads to apoptosis in yeast
• Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cA
• The RNA-binding protein SUP-12 controls muscle-specific splicing of th
• Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfol
• Protein oligomerization modulates raft partitioning and apical sorting
• Integrin v-mediated inactivation of p53 controls a MEK1-dependent mela
• MT1-MMP–dependent neovessel formation within the confines of the three
• Selective apoptosis of pluripotent mouse and human stem cells by novel
• Tumor cell traffic through the extracellular matrix is controlled by t
• Hongjun Liu, Michelle Mardahl-Dumesnil, Sean T. Sweeney, Cahir J. O'Ka
• Alan W. Dove
• Transport if loaded
• GTPase modes modeled
• SNX1 hugs the curves
• Structural and functional analysis of Nup133 domains reveals modular b
• The FG-repeat asymmetry of the nuclear pore complex is dispensable for
• Profilin for processivity
• Impact of telomerase ablation on organismal viability, aging, and tumo
• Condensin restructures chromosomes in preparation for meiotic division
• Mlp-dependent anchorage and stabilization of a desumoylating enzyme is
• Bugs to the rescue
• Protein-only prions
• Collagen for swallowing
• Retinosomes : new insights into intracellular managing of hydrophobic
• License to glue
• Corralled by septin
• Channels rush in