《细胞学杂志》.2005年.第4期

基础医学

• Nonubiquitous autophagy
• A Sisyphean helicase
• Actin adhesion controls bacterial movement
• Golgi relies on centrin
• Telomeres avoid checkpoints
• Signaling with tortoise and hare
• Pursuing the middleman : the hunt for integrins
• Frog egg extracts can do a cell's work
• Signal-mediated export of proteins from the malaria parasite to the ho
• Spore number control and breeding in Saccharomyces cerevisiae : a key
• The cell cycle–apoptosis connection revisited in the adult brain
• p62/SQSTM1 forms protein aggregates degraded by autophagy and has a pr
• Ablation of ?1 integrin in mammary epithelium reveals a key role for i
• Androgen-dependent apoptosis in male germ cells is regulated through t
• Evolution of skeletal type e–c coupling : a novel means of controlling
• Dissecting independent channel and scaffolding roles of the Drosophila
• Growth factor–induced shedding of syndecan-1 confers glypican-1 depend
• Control of lateral migration and germ cell elimination by the Drosophi
• Pleiotropic effects of FGFR1 on cell proliferation, survival, and migr
• Specific integrin and ? chain phosphorylations regulate LFA-1 activat
• Counting spores
• Seeing muscle evolution
• Clipping coreceptors
• The conserved kinase NHK-1 is essential for mitotic progression and un
• Protein synthesis persists during necrotic cell death
• Temporal separation of replication and recombination requires the intr
• DRhoGEF2 regulates actin organization and contractility in the Drosoph
• Live imaging of wound inflammation in Drosophila embryos reveals key r
• Published online 7 February 2005. doi:10.1083/jcb.200411060
• Cell migration without a lamellipodium : translation of actin dynamics
• Severing saves microtubules
• Working up to the last minute
• Another job for ?-catenin
• Lumen cues calcium release
• Ribosome does it all
• Calcium says stop
• Blood pressure and fertility
• The nucleolar origin of rRNA
• Heterochromatin is late
• Supersensitive phospholipid sensing
• Cellular organization by self-organization : mechanisms and models for
• Cells in D.C.: The American Society for Cell Biology : Washington, D.C
• A pathway for secretion
• Reduction of total E2F/DP activity induces senescence-like cell cycle
• Endoplasmic reticulum stress signaling transmitted by ATF6 mediates ap
• Microtubules shape the cell
• The discovery of tubulin
• FIAT represses ATF4-mediated transcription to regulate bone mass in tr
• Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases :
• Essential function of Drosophila Sec6 in apical exocytosis of epitheli
• Palmitoylation regulates plasma membrane–nuclear shuttling of R7BP, a
• Junctional membrane inositol 1,4,5-trisphosphate receptor complex coor
• Cdk5 protects huntingtin
• ER stress shapes muscle
• Complexes to coordinate calcium
• Make your own network
• Walk this(and that) way
• Getting ahead by staying still
• A fat ride
• Two VEGFs for big or branchy vessels
• Exocyst finds way without Rho
• Linking centrosomes and actin
• Sgk3 links growth factor signaling to maintenance of progenitor cells
• Cyclic AMP and calcium interplay as second messengers in melatonin-dep
• An ECT2–centralspindlin complex regulates the localization and functio
• An enzymatic cascade of Rab5 effectors regulates phosphoinositide turn
• Transcytosis of NgCAM in epithelial cells reflects differential signal
• Process outgrowth in oligodendrocytes is mediated by CNP, a novel micr
• Endoplasmic reticulum stress modulates the response of myelinating oli
• Histone modifications affect timing of oligodendrocyte progenitor diff
• Inducible ablation of mouse Langerhans cells diminishes but fails to a
• A mutation in dynein rescues axonal transport defects and extends the
• Deacetylate to differentiate
• RNA in the machine
• SEC18/NSF-independent, protein-sorting pathway from the yeast cortical
• Nonadhesion-based sorting
• The sticky business of discovering cadherins
• Building glial microtubules
• A hairy kinase
• Contacting the matrix
• Cohesins and breaks in yeast
• ctRNAs
• Making ROS for apoptosis
• Myosin powers cytokinesis
• FAPP2 is involved in the transport of apical cargo in polarized MDCK c
• Dendrite development : a surprising origin
• The origin recognition core complex regulates dendrite and spine devel
• A glue for heterochromatin maintenance : stable SUV39H1 binding to het
• Dynein holds still
• An AP-1/clathrin coat plays a novel and essential role in forming the
• Intraflagellar transport(IFT) during assembly and disassembly of Chla
• Reaching out for signals : filopodia sense EGF and respond by directed
• ?-Catenin controls cell sorting at the notochord–somite boundary indep
• Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex duri
• Rho GTPase regulation of exocytosis in yeast is independent of GTP hyd
• Replication complexes in neuronal morphology
• A stalled fork stalls recombination
• Lamellae lead the way
• Botulinum neurotoxin C initiates two different programs for neurite de
• Linking axonal degeneration to microtubule remodeling by Spastin-media
• Structural determinants for EB1-mediated recruitment of APC and spectr
• Inhibition of endothelial cell migration by thrombospondin-1 type-1 re
• L1, a novel target of ?-catenin signaling, transforms cells and is exp
• Coordinate control of axon defasciculation and myelination by laminin-