《细胞学杂志》.2005年.第6期

基础医学

• Fragile when condensed
• History's influence on actin
• Sticking it out with tight junctions
• Microtubules turn over rapidly
• Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of ap
• Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes
• Keratin 8 overexpression promotes mouse Mallory body formation
• Desmoplakin assembly dynamics in four dimensions : multiple phases dif
• Raf-1 the threshold of Fas sensitivity by modulating Rok- signaling
• The mammalian Scribble polarity protein regulates epithelial cell adhe
• 4?1-dependent adhesion strengthening under mechanical strain is regula
• A gas pedal for replication?
• Moving in on desmosomes
• Anchoring under shear stress
• Regulating basal body replication
• Controlling division planes
• TCRs alive on the periphery
• Less p53 for life
• G proteins find partners
• Ubiquitin/SUMO modification of PCNA promotes replication fork progress
• Tricellulin constitutes a novel barrier at tricellular contacts of epi
• The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in en
• Transition from hemifusion to pore opening is rate limiting for vacuol
• Expression of mutant huntingtin in glial cells contributes to neuronal
• Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the
• Mutational analyses reveal a novel function of the nucleotide-binding
• Distinct roles of Akt1 and Akt2 in regulating cell migration and epith
• Exocytosis in small steps
• Sticking to the nuclear envelope
• Raf-1 regulates migration
• Beating under pressure
• Acyl cycles move Ras
• The learning matrix
• Two vesicle pools for neurons
• The high mobility group transcription factor Sox8 is a negative regula
• Activity-dependent and -independent nuclear fluxes of HDAC4 mediated b
• Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cd
• Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-cont
• A small surface hydrophobic stripe in the coiled-coil domain of type I
• Raf-1 regulates Rho signaling and cell migration
• ROCK-I closure of the eyelids and ventral body wall by inducing assemb
• Two modes of exocytosis at hippocampal synapses revealed by rate of FM
• A novel mechanism of actin filament processive capping by formin : sol
• External scaffold of spherical immature poxvirus particles is made of
• Syntabulin-mediated anterograde transport of mitochondria along neuron
• ER domains
• Epigenetic manipulation of gene expression : a toolkit for cell biolog
• Breaking down symmetry
• Weaker is better
• Growth cones make proteins, too
• Putting the pinch on cell division
• Histone H1 is essential for mitotic chromosome architecture and segreg
• Actin in nonmuscle cells
• Links that separate
• Quantitative electron microscopy and fluorescence spectroscopy of the
• Conditional knockout of focal adhesion kinase in endothelial cells rev
• Tumors feed on collagen
• Cycles of muscle fusion
• Making mature attachments
• The death stops here
• Unzipped and loaded : the role of DNA helicases and RFC clamp-loading
• Sorting the mRNA overflow
• Actin in locomotion
• G protein ? interacts with the glucocorticoid receptor and suppresses
• Stress granules and processing bodies are dynamically linked sites of
• Septin-dependent compartmentalization of the endoplasmic reticulum dur
• A positive feedback loop between Dumbfounded and Rolling pebbles leads
• LIS-less neurons fall behind
• Keeping RNA away from DNA
• A Notch outlier
• Formin steps and slips
• Porterplasm" and the microtrabecular lattice
• Getting nuclei moving
• An actin ruler
• Freedom not aggregation
• The isolation of the nuclear lamina
• Turning on by turning
• An optical brain
• The eIF2 translation initiation factor travels to a cytoplasmic focus
• LIS-less neurons don't even make it to the starting gate
• LIS1 RNA interference blocks neural stem cell division, morphogenesis,
• Defective Fas expression exacerbates neurotoxicity in a model of Parki
• Stable interaction between 5?1 integrin and Tie2 tyrosine kinase recep
• Cdc42 and Par6–PKC regulate the spatially localized association of Dlg
• Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpo
• Nebulin regulates the assembly and lengths of the thin filaments in st
• Tourriere, H., K. ChA role for the eIF4E-binding protein 4E-T in P-bod
• Proline residues of transmembrane domains determine the sorting of inn
• Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic b
• Weakness as a strength
• Decondensation at the fork
• There's DNA in those organelles
• Microtubules get a name
• Cells do not relive youth
• TRPV4 channel is involved in the coupling of fluid viscosity changes t
• The AAA+ protein torsinA interacts with a conserved domain present in
• ?-site specific intrabodies to decrease and prevent generation of Alzh
• Inhibition of NGF deprivation–induced death by low oxygen involves sup
• Tadayuki Yago, Jianhua Wu, C. Diana Wey, Arkadiusz G. Klopocki, Cheng
• The exocyst component Sec5 is present on endocytic vesicles in the ooc
• Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3
• Musculin/MyoR is expressed in kidney side population cells and can reg
• Correction for Bompard and Caron, J. Cell Biol. 166(7) 957-962.
• Intracellular collagen degradation mediated by uPARAP/Endo180 is a maj