Authors' reply
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《美国医学杂志》
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
We thank the authors Sahu et al for showing an interest in our clinical brief published in IJP in February 2005.[1] We would like to clarify the points raised by them. The association of autoimmune hemolytic anemia (AIHA) with tuberculosis is extremely rare as acknowledged by the authors themselves. Early experimental studies[2] cannot be equated with actual clinical cases. Moreover, all the case reports have been in adult patients.[3],[4],[5],[6] Therefore the association of AIHA with childhood tuberculosis is even rarer.
As regards the case report by Bakshi et al[7], it was published at a time when our case report had already been submitted and was under peer review. Hence, we could not make a reference to it in our article.
We did not claim that it is the first case report of tuberculosis with AIHA, rather childhood tuberculosis with AIHA, at the time of going to press. The world childhood tuberculosis was inadvertently missed.
References
1. Gupta V, Bhatia BD. Abdominal tuberculosis with autoimmune hemolytic anemia. Indian J Pediatr 2005; 72(2) : 175-176.
2. Berkowitz, FE. Hemolysis and infection: categories and mechanisms of their interrelationship. Rev Infect Dis 1991; 1151-1162.
3. Murray HW. Transient autoimmune hemolytic anemia and pulmonary tuberculosis. N Engl J Med 1978; 299 : 488.
4. Siribaddana S, Wijesundara A. Autoimmune hemolytic anemia responding to antituberculous treatment. Tropical Doctor 1997; 27 : 243-244.
5. Kou PH, Yang PC, Kuo SS, Luh KT. Severe immune hemolytic anemia in disseminated tuberculosis with response to antituberculosis therapy. Chest 2001; 119 : 1961-1963.
6. Blanche P, Rigolet A, Massault D, Dreyfus F, Sicard D. Autoimmune hemolytic revealing military tuberculosis. J Infect Dis 2000; 40 : 292.
7. Bakshi S, Rao IS, Jain V, Arya LS. Autoimmune hemolytic anaemia complicating disseminated childhood tuberculosis. Indian J Pediatr 2004; 71 : 549-551.(Gupta V, Bhatia BD)
We thank the authors Sahu et al for showing an interest in our clinical brief published in IJP in February 2005.[1] We would like to clarify the points raised by them. The association of autoimmune hemolytic anemia (AIHA) with tuberculosis is extremely rare as acknowledged by the authors themselves. Early experimental studies[2] cannot be equated with actual clinical cases. Moreover, all the case reports have been in adult patients.[3],[4],[5],[6] Therefore the association of AIHA with childhood tuberculosis is even rarer.
As regards the case report by Bakshi et al[7], it was published at a time when our case report had already been submitted and was under peer review. Hence, we could not make a reference to it in our article.
We did not claim that it is the first case report of tuberculosis with AIHA, rather childhood tuberculosis with AIHA, at the time of going to press. The world childhood tuberculosis was inadvertently missed.
References
1. Gupta V, Bhatia BD. Abdominal tuberculosis with autoimmune hemolytic anemia. Indian J Pediatr 2005; 72(2) : 175-176.
2. Berkowitz, FE. Hemolysis and infection: categories and mechanisms of their interrelationship. Rev Infect Dis 1991; 1151-1162.
3. Murray HW. Transient autoimmune hemolytic anemia and pulmonary tuberculosis. N Engl J Med 1978; 299 : 488.
4. Siribaddana S, Wijesundara A. Autoimmune hemolytic anemia responding to antituberculous treatment. Tropical Doctor 1997; 27 : 243-244.
5. Kou PH, Yang PC, Kuo SS, Luh KT. Severe immune hemolytic anemia in disseminated tuberculosis with response to antituberculosis therapy. Chest 2001; 119 : 1961-1963.
6. Blanche P, Rigolet A, Massault D, Dreyfus F, Sicard D. Autoimmune hemolytic revealing military tuberculosis. J Infect Dis 2000; 40 : 292.
7. Bakshi S, Rao IS, Jain V, Arya LS. Autoimmune hemolytic anaemia complicating disseminated childhood tuberculosis. Indian J Pediatr 2004; 71 : 549-551.(Gupta V, Bhatia BD)