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林方才,孙 欣,赵大中,张 耀,李 光
谷氨酰胺;短肠综合征;结肠黏膜;凋亡,,],谷氨酰胺;短肠综合征;结肠黏膜;凋亡,1材料与方法,2结果,3讨论,[参考文献]
[摘要] 目的 探讨谷氨酰胺联合肠内营养对动物模型结肠黏膜凋亡的影响。方法 将大鼠随机分为3组,即正常组,模型组、谷氨酰胺组21天两个时间点进行观察。结果 谷氨酰胺组Bcl-2的平均灰度值及表达阳性的面积明显大于其他组,Bax基因蛋白平均灰度值及表达阳性的面积明显小于其他组(P<0.05)。结论 谷氨酰胺能抑制结肠黏膜细胞的凋亡,促进结肠的代偿。
[关键词] 谷氨酰胺;短肠综合征;结肠黏膜;凋亡
Influence of glutamine to apoptosis of colon mucosa rat of short bowel syndrome model
LIN Fang-cai,SUN Xin,ZHAO Da-zhong,et al.Department of General Surgery,Beijing Dianli Hospital,Beijing 100073,China
[Abstract] Objective To detect the influence of glutamine combined with enteral nutrition to apoptosis of rat colon mucosa model.Methods Rats have been divided into 3 groups ......
[关键词] 谷氨酰胺;短肠综合征;结肠黏膜;凋亡
Influence of glutamine to apoptosis of colon mucosa rat of short bowel syndrome model
LIN Fang-cai,SUN Xin,ZHAO Da-zhong,et al.Department of General Surgery,Beijing Dianli Hospital,Beijing 100073,China
[Abstract] Objective To detect the influence of glutamine combined with enteral nutrition to apoptosis of rat colon mucosa model.Methods Rats have been divided into 3 groups ......