2006年(百拇医药)

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2003年

2005年

2006年

		第1期
		第2期
		第3期
		第4期
		第5期
		第6期
		第7期
		第8期
		第9期
		第10期
		第11期
		第12期

现在位置：首页 > 医学版 > 期刊论文 > 神经病学与精神病学 > 国际神经病学神经外科学杂志 > 2006年

2006年


		第1期

07-01-01 A new type of radiosensitive T–B–NK+ severe combined immunodeficiency caused by a LIG4 mutation

07-01-01 Reversing the defective induction of IL-10–secreting regulatory T cells in glucocorticoid-resistant asthma patients

07-01-01 Microchimerism maintains deletion of the donor cell–specific CD8+ T cell repertoire

07-01-01 ERK1/2 mitogen-activated protein kinase selectively mediates IL-13–induced lung inflammation and remodeling in vivo

07-01-01 cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas

07-01-01 Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo

07-01-01 Aberrant maturation of mutant perforin underlies the clinical diversity of hemophagocytic lymphohistiocytosis

07-01-01 Anti-A?42- and anti-A?40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

07-01-01 Intramuscular viral delivery of paraplegin rescues peripheral axonopathy in a model of hereditary spastic paraplegia

07-01-01 Soy diet worsens heart disease in mice

07-01-01 Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice

07-01-01 Neuronal eotaxin and the effects of ccr3 antagonist on airway hyperreactivity and M2 receptor dysfunction

07-01-01 Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers

07-01-01 Characterization and isolation of stem cell–enriched human hair follicle bulge cells

07-01-01 B-Crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer


		第2期

07-01-01 A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y

07-01-01 Type 3 deiodinase is critical for the maturation and function of the thyroid axis

07-01-01 Toll-like receptor 2 controls expansion and function of regulatory T cells

07-01-01 Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice

07-01-01 Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin

07-01-01 Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions

07-01-01 Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis

07-01-01 Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

07-01-01 Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8+ T cell-mediated, TNF-dependent immunopathology

07-01-01 c-Fos protein as a target of anti-osteoclastogenic action of vitamin D, and synthesis of new analogs

07-01-01 Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis

07-01-01 Insulin’s direct effects on the liver dominate the control of hepatic glucose production

07-01-01 Cell-derived anaphylatoxins as key mediators of antibody-dependent type II autoimmunity in mice

07-01-01 PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury

07-01-01 Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays


		第3期

07-01-01 Signals for stress erythropoiesis are integrated via an erythropoietin receptor–phosphotyrosine-343–Stat5 axis

07-01-01 Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung

07-01-01 Loss of IRF-4–binding protein leads to the spontaneous development of systemic autoimmunity

07-01-01 Blocking the 4 integrinpaxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site

07-01-01 Similarities and differences between selective and nonselective BAFF blockade in murine SLE

07-01-01 The latency-associated nuclear antigen of Kaposi sarcoma–associated herpesvirus induces B cell hyperplasia and lymphoma

07-01-01 Prelamin A and lamin A appear to be dispensable in the nuclear lamina

07-01-01 Elastin fragments drive disease progression in a murine model of emphysema

07-01-01 Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature

07-01-01 Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154

07-01-01 Role of the forkhead protein FoxO1 in ? cell compensation to insulin resistance

07-01-01 A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

07-01-01 CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney

07-01-01 Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice

07-01-01 Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases


		第4期

07-01-01 HTLV-1 propels untransformed CD4+ lymphocytes into the cell cycle while protecting CD8+ cells from death

07-01-01 Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-?

07-01-01 1-Adrenergic receptors prevent a maladaptive cardiac response to pressure overload

07-01-01 Induction of myasthenia by immunization against muscle-specific kinase

07-01-01 CD137-mediated immunotherapy for allergic asthma

07-01-01 Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

07-01-01 Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats

07-01-01 Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

07-01-01 Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

07-01-01 Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis

07-01-01 Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

07-01-01 Cardiac mast cell-derived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/reperfusion

07-01-01 Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation

07-01-01 An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption

07-01-01 Farnesoid X receptor is essential for normal glucose homeostasis


		第5期

07-01-01 Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors

07-01-01 Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE

07-01-01 Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

07-01-01 Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

07-01-01 TGF-? signaling is required for the function of insulin-reactive T regulatory cells

07-01-01 Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

07-01-01 Optimization of a self antigen for presentation of multiple epitopes in cancer immunity

07-01-01 IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

07-01-01 Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

07-01-01 Airway smooth muscle prostaglandin-EP1 receptors directly modulate ?2-adrenergic receptors within a unique heterodimeric complex

07-01-01 Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase

07-01-01 Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2

07-01-01 HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathw

07-01-01 Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity

07-01-01 A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis


		第6期

07-01-01 Ligation of protease-activated receptor 1 enhances v?6 integrin-dependent TGF-? activation and promotes acute lung injury

07-01-01 Neutrophils and their Fc receptors are essential in a mouse model of transfusion-related acute lung injury

07-01-01 Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

07-01-01 The H1 histamine receptor regulates allergic lung responses

07-01-01 Mast cells can promote the development of multiple features of chronic asthma in mice

07-01-01 Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

07-01-01 Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans

07-01-01 Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis–induced inflammation and virulence

07-01-01 Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium

07-01-01 Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection

07-01-01 Critical role of stearoyl-CoA desaturase–1 (SCD1) in the onset of diet-induced hepatic insulin resistance

07-01-01 Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

07-01-01 Defective regulatory and effector T cell functions in patients with FOXP3 mutations

07-01-01 Corticotrophin-releasing factor receptors within the ventromedial hypothalamus regulate hypoglycemia- induced hormonal counterregulation

07-01-01 Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system


		第7期

07-01-01 Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies

07-01-01 CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

07-01-01 In vivo antigen delivery by aSalmonella typhimurium type III secretion system for therapeutic cancer vaccines

07-01-01 Ghrelin action in the brain controls adipocyte metabolism

07-01-01 KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice

07-01-01 Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

07-01-01 KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice

07-01-01 Ghrelin action in the brain controls adipocyte metabolism

07-01-01 Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity

07-01-01 KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice

07-01-01 Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

07-01-01 Possible axonal regrowth in late recovery from the minimally conscious state

07-01-01 The leak stops here: platelets as delivery vehicles for coagulation factors

07-01-01 Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption ofSmad4 andPten in mice

07-01-01 CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy


		第8期

07-01-01 Connexin 43 mediates spread of Ca2+ -dependent proinflammatory responses in lung capillaries

07-01-01 Mosaicism of activatingFGFR3 mutations in human skin causes epidermal nevi

07-01-01 Nicotine induces cell proliferation by ?-arrestin–mediated activation of Src and Rb–Raf-1 pathways

07-01-01 Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice

07-01-01 HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease

07-01-01 A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN–based vaginal microbicide

07-01-01 Anaphylactic shock depends on PI3K and eNOS-derived NO

07-01-01 Inhibition of T cell activation and autoimmune diabetes using a B cell surface–linked CTLA-4 agonist

07-01-01 MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

07-01-01 Proteinuria precedes podocyte abnormalities inLamb2–/– mice, implicating the glomerular basement membrane as an albumin barrier

07-01-01 Mutual repression between steroid and xenobiotic receptor and NF-B signaling pathways links xenobiotic metabolism and inflammation

07-01-01 Antisense oligonucleotide therapy for neurodegenerative disease

07-01-01 Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production

07-01-01 Early G2/M checkpoint failure as a molecular mechanism underlying etoposide-induced chromosomal aberrations

07-01-01 Inflammation and insulin resistance


		第9期

07-01-01 Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block

07-01-01 Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

07-01-01 Role of IFN- in induction of Foxp3 and conversion of CD4+ CD25– T cells to CD4+ Tregs

07-01-01 Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans

07-01-01 Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling

07-01-01 Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

07-01-01 The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity

07-01-01 FcRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation

07-01-01 TRAIL receptor–mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality

07-01-01 Bone protection by estrens occurs through non–tissue-selective activation of the androgen receptor

07-01-01 Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycar

07-01-01 PTEN inhibits IL-2 receptor–mediated expansion of CD4+ CD25+ Tregs

07-01-01 Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M

07-01-01 Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines

07-01-01 Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels


		第10期

07-01-01 In This Issue

07-01-01 Response to Zhou et al.

07-01-01 The troubled dream of genetic medicine

07-01-01 Yellow fever

07-01-01 The physician-scientist, the state, and the oath: thoughts for our times

07-01-01 Deiodinases: implications of the local control of thyroid hormone action

07-01-01 T cell activation altersintestinal structure and function

07-01-01 Pili prove pertinent to enterococcal endocarditis

07-01-01 Imaging tumor angiogenesis

07-01-01 Myeloid suppressor cells regulate the adaptive immune response to cancer

07-01-01 To be or not to be B7

07-01-01 Children are not little adults: just ask their hematopoietic stem cells

07-01-01 Calcineurin/Nfat signaling is required for perinatal lung maturation and function

07-01-01 Rapid vascular regrowth in tumors after reversal of VEGF inhibition

07-01-01 Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid


		第11期

07-01-01 Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

07-01-01 Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration

07-01-01 NF-B regulation of endothelial cell function during LPS-induced toxemia and cancer

07-01-01 NF-B2 is required for the establishment of central tolerance through an Aire-dependent pathway

07-01-01 Mutation of ?-glucosidase 2 causes glycolipid storage disease and impaired male fertility

07-01-01 Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice

07-01-01 Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection

07-01-01 TLR4 links innate immunity and fatty acid–induced insulin resistance

07-01-01 Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus

07-01-01 Rai1 duplication causes physical and behavioral phenotypes in a mouse model of dup(17)(p11.2p11.2)

07-01-01 Impaired regulation of NF-B and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

07-01-01 Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone ? receptor inhibits mitotic progression

07-01-01 Deficiency in neuronal TGF-? signaling promotes neurodegeneration and Alzheimer’s pathology

07-01-01 Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice


		第12期

07-01-01 Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and Bcl2A1 as critical target genes

07-01-01 Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis

07-01-01 Proteasome-mediated degradation of IB and processing of p105 in Crohn disease and ulcerative colitis

07-01-01 Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice

07-01-01 Indoleamine 2,3-dioxygenase–expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection

07-01-01 Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

07-01-01 Rosiglitazone promotes development of a novel adipocyte population from bone marrow–derived circulating progenitor cells

07-01-01 Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice

07-01-01 Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis

07-01-01 Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

07-01-01 Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy

07-01-01 Acute HIV revisited: new opportunities for treatment and prevention

07-01-01 Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism

07-01-01 Autophagy in cell death: an innocent convict?